uncoupling agents การใช้

Salicylic acid is also an uncoupling agent and will decrease production of ATP and increase body temperature if taken in excess.
:: Well, uncoupling agents are defined by their ability to ( essentially ) break down the electrical resistance of the mitochondrial membrane e . g . by acting as proton ionophores, discharging its energy unproductively.
Given that hypothermia results from heat loss that outstrips the body's rate of thermogenesis, and that the main effect of uncoupling agents like 2, 4-Dinitrophenol is to greatly increase the rate of thermogenesis to far above its normal range, could 2, 4-DNP and \ or other uncouplers be useful in counteracting severe hypothermia?
:: Hmmm, we should have an article uncoupling agent . . . note that there have been " many " brilliant ideas for weight loss invented that have been withdrawn after they turned out to kill lots of people . ( I can think of amphetamines, Phen-fen and ephedra off hand, but I think there are more ! ) talk ) 13 : 05, 13 April 2016 ( UTC)